Tokai University Hospital

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Clinical department/department

Breast Surgery

Greetings

Our department is a certified facility of the Japanese Breast Cancer Society and a certified training facility of the Japanese Society of Clinical Oncology, and we perform surgery on approximately 300 breast cancer patients annually. We also receive referrals from all over Japan for the treatment of patients with advanced or recurrent breast cancer. Our principle is to provide medical care based on scientific evidence. We are in a pioneering position in immunotherapy and molecular targeted therapy, and we actively participate in the development of new therapeutic drugs and medical technologies.

Treatment plans for patients are decided through joint conferences with the pathology, radiology, and ultrasound departments. Various prognostic factors are analyzed from the collected cancer tissue using immunohistochemistry and molecular biology methods. Then, in consultation with the patient and their family, adjuvant therapy is administered to prevent recurrence. In addition, for patients with recurrence, we formulate aggressive treatment strategies and have achieved good treatment outcomes.

Director of Breast Surgery Department
Naoki Niikura

Treatment details

Our department treats both malignant and benign breast diseases, with five breast specialists providing breast cancer care. We also have three cancer chemotherapy specialists on staff, who provide chemotherapy for other malignant tumors. We actively provide physical and psychological palliative care for patients and their families from the time of diagnosis of malignant disease through to the terminal stage, striving to provide medical care that allows patients to receive cancer treatment with peace of mind. We also work in collaboration with Department of Genetics to handle familial tumors and cancer genome testing.

<Mammary gland disease>
Specialization is important in the diagnosis and treatment of breast cancer, and the content is improving every day. Our hospital plays a central role in this field in the western Kanagawa region. The breast disease treatment policy is centered on breast specialists, and we hold joint conferences every week with pathologists, radiologists, certified radiologists, and ultrasound technicians to provide team medical care.

<Diagnosis>
If necessary, we aim to provide a prompt diagnosis at the first visit by performing mammography, breast ultrasound, cytology, and tissue biopsy.

<Surgery/post-operative therapy>
Before surgery, we inform the patient of the disease, perform a high-resolution breast MRI scan to determine the appropriate extent of resection, explain the advantages and disadvantages of breast-conserving surgery and mastectomy, and present the available surgical procedures to the patient for selection. From detailed intraoperative and postoperative pathological examinations to scientifically based aggressive postoperative drug therapy, we provide everything on an outpatient basis. Furthermore, if breast reconstruction is desired, we work with plastic surgery to perform rectus abdominis and latissimus dorsi flap reconstructions and implant reconstructions.

<Treatment for advanced and recurrent breast cancer>
For the treatment of advanced or recurrent breast cancer, we provide tailor-made treatment that takes into account the wishes and circumstances of each individual patient, while also adhering to the latest evidence-based principles.

We also participate in development trials of new drugs and many clinical trials on a global scale, giving us more treatment options than other facilities and striving to improve treatment outcomes for cases in which existing treatments are ineffective.

<Cancer Genomic Medicine>
Cancer genomic medicine is a type of personalized medicine that uses the patient's cancer cells to examine genetic changes and provide treatment tailored to the characteristics of each individual's cancer. Our department at our hospital is involved in cancer genomic medicine for various malignant tumors, not just breast cancer, and we select and propose treatments that are tailored to the characteristics of each patient's cancer.

Main target diseases

─Mammary gland disease─
Early breast cancer, advanced/recurrent breast cancer, mastopathy, mastitis, breast abscess, fibroadenoma, phyllodes tumor, gynecomastia, etc.

—Other Malignant Tumors—
Drug therapy for cancer of unknown primary origin and other malignant tumors

Main medical achievements

Our department handles both malignant and benign breast diseases, with a particular focus on breast cancer. In 2025, our department performed 348 surgeries (327 breast cancer surgeries under general anesthesia). We performed 150 breast-conserving surgeries, 177 mastectomies (21 with breast reconstruction), and 243 sentinel lymph node biopsies. We had 626 new outpatients. Our well-equipped outpatient chemotherapy center has provided safe, reliable, and rapid treatment to a total of 2,961 patients by dedicated physicians, nurses, and pharmacists. In 2025, we undertook 28 clinical trials, and many clinical trials are currently underway, particularly for advanced/recurrent breast cancer and luminal early-stage breast cancer.

Doctor List

Department Head: Naoki Niikura
Ward 12B Chief Physician: Takuho Okamura

Outpatient: 0463(93)1121 extension 6211

Professor Naoki Niikura

Specialization

Breast cancer chemotherapy

Specialist

Board Certified Surgeon in general surgery. Board Certified Surgeon in breast surgery. Board Certified Medical Oncology.

Specialized Areas

Surgery for breast cancer, biological diagnosis and treatment of advanced and recurrent breast cancer, and multidisciplinary treatment of bone metastases and brain metastases.

Outpatient medical day

Monday and Tuesday

Lecturer: Takuho Okamura

Specialization

Breast cancer chemotherapy

Specialist

Board Certified Surgeon in general surgery. Board Certified Surgeon in breast surgery. Board Certified Medical Oncology.

Specialized Areas

Surgery, medical therapy, and supportive care for breast cancer

Outpatient medical day

Tuesday and Friday

Associate Professor Toru Hanamura

Specialization

mammary gland

Specialist

Board Certified Surgeon in general surgery. Board Certified Surgeon in breast surgery.

Specialized Areas

Diagnosis and treatment of breast diseases

Outpatient medical day

Wednesday

Mayako Terao (Instructor)

Specialization

Breast cancer chemotherapy

Specialist

Certified Internal Medicine Specialist (Japanese Society of Internal Medicine) / Certified Mammography Reader / Certified Oncologist / Certified Oncologist and Instructor (Japanese Society of Clinical Oncology) / Certified Breast Cancer Instructor and Specialist (Japanese Breast Cancer Society) / Certified Hereditary Tumor Specialist

Specialized Areas

Diagnosis and treatment of breast diseases, hereditary breast cancer

Outpatient medical day

Mondays and Thursdays

Assistant Professor Rie Ishida

Specialization

mammary gland

Specialist

Certified mammogram reader

Specialized Areas

Diagnosis and treatment of breast diseases

Outpatient medical day

Wednesday and Thursday

Assistant Professor Saeko Nakagawa

Specialization

mammary gland

Specialist

Board Certified Surgeon in Internal medicine.

Specialized Areas

Diagnosis and treatment of breast diseases

Kozue Yokoyama Graduate School

Specialization

mammary gland

Specialist

Board Certified Surgeon in Internal medicine. Board Certified Surgeon in breast surgery.

Specialized Areas

Diagnosis and treatment of breast diseases

Outpatient medical day

Thursday

Assistant Professor Saori Takahashi

Specialization

mammary gland

Specialist

Board Certified Surgeon in general surgery.

Specialized Areas

Diagnosis and treatment of breast diseases

Outpatient medical day

Tuesdays, Thursdays

Assistant Professor Hikari Kiyohara

Specialization

mammary gland

Specialist

Board Certified Surgeon in Internal medicine.

Specialized Areas

Diagnosis and treatment of breast diseases

Outpatient medical day

Mondays and Wednesdays