Greetings
Our neurology department treats approximately 700-750 inpatients annually, making us one of the leading neurology departments among university hospitals in Japan. Stroke accounts for approximately half of all inpatients, and we provide thrombolysis and endovascular therapy for hyperacute cerebral infarction 24/7. For patients with Parkinson’s disease, we offer not only oral medications but also advanced treatments such as deep brain stimulation (DBS), levodopa-carbidopa intestinal therapy (LCIG), and continuous subcutaneous infusion therapy (Vialev), aiming to improve functional outcomes for each individual patient. As a core hospital for the prefecture's Dementia Treatment Department, we collaborate with local medical institutions to provide dementia care. In addition to neurologists, we also have stroke specialists, endovascular neurologists, and headache specialists on staff, providing state-of-the-art treatment both domestically and internationally. In addition to the above, we also provide care for a variety of intractable neurological disorders, such as multiple sclerosis and genetic disorders, so please feel free to visit the Department of Neurology.
Chief Department of Neurology
Eiichiro Nagata
Treatment details
Stroke accounts for approximately half of all cases in our department. We provide comprehensive neurological care, from dynamic illnesses (acute conditions) such as acute cerebrovascular disorders to static illnesses (chronic conditions) such as degenerative and immune disorders and peripheral neuropathy. For cerebral infarction in particular, acute treatments such as intravenous rt-PA therapy and endovascular treatment in collaboration with Neurosurgery. We perform MRI, MR angiography, carotid artery and cardiac echocardiography, and Holter ECG in almost all cases, and transesophageal echocardiography as needed to select the appropriate treatment. For cryptogenic cerebral infarction, we implants loop recorder (Reveal LINQ) to actively search for the source of the embolism.
In addition to the latest drug treatments for Parkinson's disease, we have also introduced the latest treatments for refractory cases, such as deep brain stimulation (DBS), levodopa-carbidopa enteral therapy (LCIG), and continuous subcutaneous infusion therapy (Vialev).For neuroimmune diseases such as multiple sclerosis and neuromyelitis optica, specialists provide steroid pulse therapy as an acute treatment and various DMDs (disease-modifying drugs) to prevent relapse, including the latest medications. We also provide the latest antibody therapies developed in recent years for patients with autoimmune neurological disorders.
Regarding dementia, our hospital is the only core Dementia Treatment Department in the prefecture, and we cooperate with other dementia centers and local medical institutions. We also use PET scans to diagnose Alzheimer's disease, and have recently started antibody therapy for mild cognitive impairment (MCI) in Alzheimer's disease.
In peripheral neuropathy, patients with Guillain-Barré syndrome and CIDP are actively treated with IVIg and maintenance, subcutaneous immunboglobulin (SCIG), and anti-FcRn antibody therapy.
In addition, for migraines, a detailed diagnosis is made by a headache specialist and treatment is provided using the latest CGRP-related antibody therapies, etc. When patients are transported by ambulance due to status epilepticus, if their state of consciousness is poor, they are placed under ICU care and undergo detailed tests such as EEG monitoring to provide appropriate treatment.
In addition, for infectious diseases such as meningitis, we perform diagnostic imaging and cerebrospinal fluid tests early, and we also provide treatment for rare diseases such as familial amyloid polyneuropathy (FAP) using the latest nucleic acid medicines.
We actively conduct clinical trials for various diseases in order to provide the latest treatment techniques.In addition to the above, we also provide medical care to treat various intractable neurological diseases, including hereditary disorders, and genetic counseling is also provided by clinical geneticists.
Main target diseases
Our practice covers a wide range of neurological conditions, including cerebral infarction and transient ischemic attacks (TIA), cerebral hemorrhage, bacterial and viral meningitis, herpes encephalitis, neuroinfectious diseases such as prion diseases including Creutzfeldt-Jakob disease, degenerative diseases such as Parkinson's disease and spinocerebellar degeneration, dementia diseases such as Alzheimer's disease and dementia with Lewy bodies, demyelinating diseases (neuroimmune diseases) such as multiple sclerosis and acute disseminated encephalomyelitis (ADEM), functional disorders such as epilepsy, hemifacial spasm, and headaches, peripheral neuropathy, myelopathy, ALS, Guillain-Barré syndrome, and CIDP, muscle diseases, rare diseases such as familial amyloidotic neuropathy, and general neurological conditions.
Main medical achievements
*Annual number of hospitalized patients at the affiliated hospital: 804 (From January 2024 to December 2024)
| disease | |
| Cerebrovascular disease | 353例 |
| Spinal cord and spinal disorders | 36例 |
| Epilepsy | 93例 |
| Encephalitis/Meningitis | 32例 |
| Neurodegenerative diseases | 12例 |
| Dementia | 5例 |
| Amyotrophic lateral sclerosis | 19例 |
| Multiple sclerosis/neuromyelitis optica-related disorders | 77例 |
| Peripheral nerve disease (including Guillain-Barré syndrome) | 33例 |
| Myasthenia gravis | 45例 |
| Muscle disease | 13例 |
| Parkinson's disease | 32例 |
| Metabolic diseases/toxicity | 3例 |
| Creutzfeldt-Jakob disease | 3例 |
| Others | 48例 |
Photo: An illustrative case of a patient with acute cerebral infarction. The patient presented with complete right-sided hemiplegia and was transported to our hospital 33 minutes after onset. A diffusion-weighted MRI (DWI) of the head on arrival revealed high signal intensity in the left basal ganglia, and magnetic resonance angiography (MRA) revealed occlusion of a middle cerebral artery. Intravenous thrombolysis was initiated 45 minutes after arrival, and endovascular treatment was performed 78 minutes later, achieving complete recanalization 138 minutes after onset. Atrial fibrillation was detected after admission, leading to a diagnosis of cardiogenic cerebral embolism due to atrial fibrillation. A novel oral anticoagulant was prescribed, and the patient was discharged home two weeks later, able to walk independently. As described above, this case highlights the effectiveness of acute treatment with thrombolytic therapy and endovascular treatment.
Doctor List
Department Head: Eiichiro Nagata
Assistant Chief Physician of Ward 10A: Atsushi Mizuma
Chief of Ward 10B: Yoichi Onuki
Clinical Department URL: https://www.fuzoku-hosp.tokai.ac.jp/service/shinkei-naika/
http://neurol.med.u-tokai.ac.jp/
Outpatient: 0463 (93) 1121 extension 6401
Professor Eiichiro Nagata
| Specialization | Headache, Neuromuscular disorders, Motor neuron diseases |
|---|---|
| Specialist | Certified Internal Medicine Doctor/ Certified by Neurology Specialist/ Stroke Specialist /Headache Specialist |
| Specialized Areas | Diagnosis and treatment of headaches, diagnosis and treatment of muscle and peripheral neuropathy, neuroimmune disorders, motor neuron diseases |
| Outpatient medical day | Tuesdays, Thursdays |
Professor Takato Abe
| Specialization | Cerebrovascular disease, Dementia |
|---|---|
| Specialist | General Internal Medicine Medicine Specialist, Certified by the Japanese Society of Internal Medicine, Neurology Specialist, Stroke Specialist, and Dementia Specialist |
| Specialized Areas | Thrombolytic therapy for acute cerebral infarction, antiplatelet therapy, prevention of recurrence, diagnosis and treatment of dementia |
| Outpatient medical day | Monday and Friday |
Associate Professor Yoichi Onuki
| Specialization | Cerebrovascular disease |
|---|---|
| Specialist | Certified Internal Medicine Society Doctor/Neurology Specialist/Stroke Specialist/ Neuroendovascular Treatment Specialist |
| Specialized Areas | Endovascular treatment and diagnosis and treatment of cerebral infarction |
| Outpatient medical day | Thursday and Friday |
Associate Professor Yuko Onuki *
| Specialization | Neurological intractable diseases, Cerebrovascular disorders |
|---|---|
| Specialist | Certified Internal Medicine Doctor/Certified by Neurologist/Clinical Genetics Specialist |
| Specialized Areas | Genetic counseling for intractable neurological diseases, diagnosis and treatment of cerebrovascular disorders |
| Outpatient medical day | Monday |
Associate Professor Atsushi Mizuma
| Specialization | Cerebrovascular disease |
|---|---|
| Specialist | General Internal MedicineGeneral Internal Medicine Specialist of the Japanese Society of Internal Medicine / Certified by Neurology Specialist / Stroke Specialist / Headache / Dementia Specialist / Neuroimmunology Specialist |
| Specialized Areas | Diagnosis and treatment of cerebral infarction, diagnosis and treatment of headaches |
| Outpatient medical day | Monday, Wednesday, Thursday |
Lecturer: Mitsuhiko Yamano *
| Specialization | Epilepsy Internal Medicine Society Certified Doctor/Neurologist/Epilepsy Specialist |
|---|---|
| Specialist | Certified Internal Medicine Doctor/Certified by Neurology Specialist/ Epilepsy Specialist |
| Specialized Areas | Epilepsy diagnosis and treatment |
| Outpatient medical day | Friday and Saturday |
Assistant Professor Taira Nakayama
| Specialization | Cerebrovascular disease |
|---|---|
| Specialist | Certified Internal Medicine Doctor/Certified by Neurology Specialist/ Stroke Specialist |
| Specialized Areas | Diagnosis and treatment of cerebrovascular disorders |
| Outpatient medical day | Wednesdays, Fridays (first visit: 2nd and 4th weeks), Saturdays |
Assistant Professor Shizuka Nezu
| Specialization | General neurology, cerebrovascular disorders |
|---|---|
| Specialist | General Internal Medicine Certified by Neurology Specialist/ |
| Specialized Areas | Diagnosis and treatment of cerebrovascular disorders, neuroimmune diseases |
| Outpatient medical day | Saturday |
Assistant Professor Reina Kawamura
| Specialization | General Neurology |
|---|---|
| Specialist | General Internal Medicine,/ Certified by Neurology Specialist/ Specialist in Electromyography and Nerve Conduction, Japan Society of Clinical Neurophysiology |
| Specialized Areas | Diagnosis and treatment of cerebrovascular disorders, Neuroimmune diseases, Peripheral neuropathy |
| Outpatient medical day | Thursday (re-visit: 1st, 3rd, 5th week) / Friday (initial visit: 1st, 3rd, 5th week) |
Assistant Professor Jun Togashi
| Specialization | General Neurology |
|---|---|
| Specialist | Certified by Internal Medicine Specialist |
| Outpatient medical day | Tuesday |
Assistant Professor Naoto Suzuki
| Specialization | General Neurology |
|---|---|
| Specialist | Certified by Internal Medicine Specialist |
| Outpatient medical day | Friday |
Assistant Professor Masanari Shirafuji
| Specialization | General Neurology |
|---|---|
| Outpatient medical day | Wednesday |
Assistant Professor Yuichi Ito
| Specialization | General Neurology |
|---|---|
| Outpatient medical day | Saturday |
Ryoko Imazeki (Part-time doctor) *
| Specialization | Cerebrovascular disease, dementia diagnosis and treatment |
|---|---|
| Specialist | General Internal Medicine / Certified byNeurology Specialist/Stroke Specialist / Headache Specialist/ Dementia Specialist |
| Specialized Areas | Diagnosis and treatment of dementia and headaches |
| Outpatient medical day | Monday (Afternoon) |
*These doctors' outpatient appointments cannot be booked directly from outside.