Tokai University Hospital

Font size
ENGLISH JAPANESE
ENGLISH
JAPANESE
For visitors
For medical professionals
Hospital Information
Clinical department/department
Recruitment Information

phone

Web
reservation

Clinical department/department

Department of Neurology

Greetings

Our department provides specialized medical care across the entire field of Department of Neurology, from acute illnesses such as stroke to neurodegenerative diseases, neuroimmunological diseases, dementia, and peripheral neuropathy. We admit approximately 800 inpatients annually and have one of the leading clinical records among university hospital Department of Neurology in Japan.

In addition to providing highly specialized treatment 24 hours a day for acute stroke, we also provide medical care for rare neurological diseases such as Parkinson's disease, multiple sclerosis, and myasthenia gravis, based on the latest knowledge from Japan and abroad, and propose optimal treatments aimed at improving function. In the field of dementia care, which has become a social problem in our aging society, as a core Dementia Treatment Department in Kanagawa Prefecture, we work closely with local medical institutions to build a comprehensive medical system from early diagnosis to treatment and support for daily living.

Our department has a diverse team of specialists, including stroke specialists, endovascular neurosurgery specialists, headache specialists, and neuroimmunology/genetics specialists, providing advanced and cutting-edge medical care for a wide range of neurological diseases. We also promote translational research that integrates basic research and clinical practice, and actively engage in the development of new treatments and clinical trials. This allows us to quickly deliver the most advanced medical care to our patients.

We will continue to strive to provide the best possible medical care for our patients, based on the latest evidence and technology.

Head of the Department of Neurology
Takato Abe

Treatment details

In our department, stroke accounts for approximately half of all cases, and we provide medical care across the entire field of Department of Neurology, from dynamic diseases such as acute cerebrovascular disorders to static diseases such as neurodegenerative diseases, neuroimmunological diseases, and peripheral neuropathy.

In particular, for cerebral infarction, we provide advanced acute care 24 hours a day in cooperation with the emergency medical center and Neurosurgery, including rt-PA intravenous therapy and endovascular treatment by endovascular specialists. In almost all cases, we perform MRI, MR angiography, carotid artery and cardiac echocardiography, and Holter ECG, and add transesophageal echocardiography as needed to determine the appropriate treatment plan. Furthermore, for cryptogenic cerebral infarction, we implant an implantable electrocardiogram recorder (Reveal LINQ) to actively search for the source of the embolus.

For Parkinson's disease, in addition to the latest drug therapies, we have introduced advanced treatments such as deep brain stimulation (DBS), enteral levodopa/carbidopa therapy (LCIG), and continuous subcutaneous infusion therapy (Vialev) for refractory cases. For neuroimmunological diseases such as multiple sclerosis and neuromyelitis optica, in addition to acute treatments such as steroid pulse therapy, specialists provide treatment based on the latest knowledge, including various disease-modifying drugs (DMDs) aimed at preventing relapses. We also offer advanced treatments for myasthenia gravis, including antibody therapies developed in recent years.

In dementia care, our hospital, as the only core Dementia Treatment Department in the prefecture, promotes collaboration with various facilities and local medical institutions throughout the prefecture. We utilize PET scans for the diagnosis of Alzheimer's disease and also offer novel antibody therapies for mild cognitive impairment (MCI).

For peripheral neuropathy, we actively implement immunoglobulin maintenance therapy, home self-injection (SCIG), and anti-FcRn antibody therapy for Guillain-Barré syndrome and CIDP. For migraines, we provide the latest treatments, such as CGRP-related antibody preparations, based on precise diagnoses by headache specialists. For status epilepticus, in severe cases, we perform electroencephalography (EEG) and other tests under ICU management to provide appropriate treatment.

Furthermore, for infectious diseases such as meningitis, we strive for early diagnosis and treatment by performing rapid imaging and cerebrospinal fluid examinations. In addition, we offer the latest treatments, including nucleic acid drugs, for rare diseases such as familial amyloid neuropathy (FAP).

Our department actively conducts clinical trials for various diseases in order to bring the latest treatment technologies back to patients. Furthermore, we have established a system capable of handling a wide range of intractable neurological diseases, including hereditary disorders, and we also provide genetic counseling by clinical genetic specialists.

Main target diseases

We treat a wide range of neurological conditions, including cerebral infarction and transient ischemic attacks (TIAs), cerebral hemorrhage, bacterial and viral meningitis, herpes encephalitis, prion diseases such as Creutzfeldt-Jakob disease, degenerative diseases such as Parkinson's disease and spinocerebellar degeneration, dementias such as Alzheimer's disease and Lewy body dementia, demyelinating diseases (neuroimmunological diseases) such as multiple sclerosis and acute disseminated encephalomyelitis (ADEM), functional disorders such as epilepsy, facial spasms, and headaches, peripheral neuropathy such as myopathy, ALS, Guillain-Barré syndrome, and CIDP, muscle diseases, rare diseases such as familial amyloid neuropathy, and general neurological conditions.

Main medical achievements

*Annual number of hospitalized patients at the affiliated hospital: 804 (From January 2024 to December 2024)

disease
Cerebrovascular disease 353例
Spinal cord and spinal disorders 36例
Epilepsy 93例
Encephalitis/Meningitis 32例
Neurodegenerative diseases 12例
Dementia 5例
Amyotrophic lateral sclerosis 19例
Multiple sclerosis/neuromyelitis optica-related disorders 77例
Peripheral nerve disease (including Guillain-Barré syndrome) 33例
Myasthenia gravis 45例
Muscle disease 13例
Parkinson's disease 32例
Metabolic diseases/toxicity 3例
Creutzfeldt-Jakob disease 3例
Others 48例

Photo: An illustrative case of a patient with acute cerebral infarction. The patient presented with complete right-sided hemiplegia and was transported to our hospital 33 minutes after onset. A diffusion-weighted MRI (DWI) of the head on arrival revealed high signal intensity in the left basal ganglia, and magnetic resonance angiography (MRA) revealed occlusion of a middle cerebral artery. Intravenous thrombolysis was initiated 45 minutes after arrival, and endovascular treatment was performed 78 minutes later, achieving complete recanalization 138 minutes after onset. Atrial fibrillation was detected after admission, leading to a diagnosis of cardiogenic cerebral embolism due to atrial fibrillation. A novel oral anticoagulant was prescribed, and the patient was discharged home two weeks later, able to walk independently. As described above, this case highlights the effectiveness of acute treatment with thrombolytic therapy and endovascular treatment.

Doctor List

Department Head: Takato Abe
Deputy Chief Physician of Ward 10A: Atsushi Mizuma
Chief Physician of Ward 10B: Yoichi Onuki

Outpatient: 0463 (93) 1121 extension 6401

Professor Eiichiro Nagata

Specialization

Headache, Neuromuscular disorders, Motor neuron diseases

Specialist

Certified Internal Medicine Doctor/ Certified by Neurology Specialist/ Stroke Specialist /Headache Specialist

Specialized Areas

Diagnosis and treatment of headaches, diagnosis and treatment of muscle and peripheral neuropathy, neuroimmune disorders, motor neuron diseases

Outpatient medical day

Mondays and Thursdays

Professor Takato Abe

Specialization

Cerebrovascular disease, Dementia

Specialist

General Internal Medicine Medicine Specialist, Certified by the Japanese Society of Internal Medicine, Neurology Specialist, Stroke Specialist, and Dementia Specialist

Specialized Areas

Thrombolytic therapy for acute cerebral infarction, antiplatelet therapy, prevention of recurrence, diagnosis and treatment of dementia

Outpatient medical day

Tuesday and Friday

Associate Professor Yuko Onuki *

Specialization

Neurological intractable diseases, Cerebrovascular disorders

Specialist

Certified Internal Medicine Doctor/Certified by Neurologist/Clinical Genetics Specialist

Specialized Areas

Genetic counseling for intractable neurological diseases, diagnosis and treatment of cerebrovascular disorders

Outpatient medical day

Monday

Associate Professor Yoichi Onuki

Specialization

Cerebrovascular disease

Specialist

Certified Internal Medicine Society Doctor/Neurology Specialist/Stroke  Specialist/ Neuroendovascular Treatment Specialist

Specialized Areas

Endovascular treatment and diagnosis and treatment of cerebral infarction

Outpatient medical day

Wednesday and Thursday

Associate Professor Atsushi Mizuma

Specialization

Extrapyramidal disorders, neuroimmunological disorders

Specialist

General Internal MedicineGeneral Internal Medicine Specialist of the Japanese Society of Internal Medicine / Certified by Neurology Specialist / Stroke Specialist / Headache / Dementia Specialist / Neuroimmunology Specialist

Specialized Areas

Diagnosis and treatment of Parkinson's disease

Outpatient medical day

Monday, Wednesday, Thursday

Lecturer: Mitsuhiko Yamano *

Specialization

Epilepsy Internal Medicine Society Certified Doctor/Neurologist/Epilepsy Specialist

Specialist

Certified Internal Medicine Doctor/Certified by Neurology Specialist/ Epilepsy Specialist

Specialized Areas

Epilepsy diagnosis and treatment

Outpatient medical day

Friday and Saturday

Assistant Professor Taira Nakayama

Specialization

Cerebrovascular disease

Specialist

Certified Internal Medicine Doctor/Certified by Neurology Specialist/ Stroke Specialist

Specialized Areas

Diagnosis and treatment of cerebrovascular disorders

Outpatient medical day

Wednesday and Friday

Assistant Professor Shizuka Nezu

Specialization

General neurology, cerebrovascular disorders

Specialist

General Internal Medicine Certified by  Neurology Specialist/ 

Specialized Areas

Diagnosis and treatment of cerebrovascular disorders, neuroimmune diseases

Outpatient medical day

Saturday

Assistant Professor Jun Togashi

Specialization

General Neurology

Specialist

Certified by Internal Medicine Specialist

Outpatient medical day

Tuesday

Assistant Professor Naoto Suzuki

Specialization

General Neurology

Specialist

Certified by Internal Medicine Specialist

Outpatient medical day

Friday

Assistant Professor Masanari Shirafuji

Specialization

General Neurology

Outpatient medical day

Wednesday

Assistant Professor Yuichi Ito

Specialization

General Neurology

Outpatient medical day

Thursday

Ryoko Imazeki (Part-time doctor) *

Specialization

Cerebrovascular disease, dementia diagnosis and treatment

Specialist

General Internal Medicine / Certified byNeurology Specialist/Stroke Specialist / Headache Specialist/ Dementia Specialist

Specialized Areas

Diagnosis and treatment of dementia and headaches

Outpatient medical day

Monday (Afternoon)

*These doctors' outpatient appointments cannot be booked directly from outside.